Custom 1H/13C Coil Support
Structure for supporting a 14cm 1H/13C coil within a 20cm bore. PVC pipes are used to insert the coil and structure, small tabs hold the structure in place by attaching to the lip of the gradient insert.
Posts by Collection
models
Rat Bite Bar
A bite bar for rats under anesthesia.
Bruker Cardiac Coil Support
Structure for supporting a cardiac surface coil within a quadrature volume coil.
Long, Single Mouse Cradle
A long mouse cradle for use with a custom volume coil. Cutouts for anesthesia and waste anesthetic gas scavenging.
Syringe Pump
Syringe pump for six in-scanner injections of two agents (e.g. MR contrast and PET tracer). This was drawn as a concept and never printed or tested.
Six-Mouse Cradle (PET + fMRI)
A six-mouse cradle for simultaneous PET and MR brain imaging. Made in collaboration with Dr. Joseph Mandeville.
portfolio
Portfolio item number 1
Short description of portfolio item number 1
Portfolio item number 2
Short description of portfolio item number 2
publications
Accelerated and quantitative three‐dimensional molecular MRI using a generative adversarial network
Published in Magnetic Resonance in Medicine, 2022
Three‐dimensional CEST and MT magnetic resonance fingerprinting (MRF) datasets of L‐arginine phantoms, whole‐brains, and calf muscles from healthy volunteers, cancer patients, and cardiac patients were acquired using 3T clinical scanners at three different sites, using three different scanner models and coils. A saturation transfer‐oriented generative adversarial network (GAN‐ST) supervised framework was then designed and trained to learn the mapping from a reduced input data space to the quantitative exchange parameter space, while preserving perceptual and quantitative content.
Recommended citation: Weigand-Whittier J, et al. (2022). "Accelerated and quantitative three‐dimensional molecular MRI using a generative adversarial network" Magn Reson Med. 89(1901-1914).
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Ungated, plug-and-play preclinical cardiac CEST-MRI using radial FLASH with segmented saturation
Published in Magnetic Resonance in Medicine, 2024
The proposed method consists of segmented saturation modules with radial FLASH readouts and golden angle progression. The segmented saturation blocks drive the system to steady-state, and because center k-space is sampled repeatedly, steady-state saturation dominates contrast during gridding and reconstruction. Ten complete Z-spectra were acquired in healthy mice using both ECG and respiratory-gated and ungated methods. Z-spectra were also acquired at multiple saturation B1 values to optimize for amide and Cr contrasts.
Recommended citation: Weigand-Whittier J, et al. (2024). "Ungated, plug-and-play preclinical cardiac CEST-MRI using radial FLASH with segmented saturation" Magn Reson Med. 93(1793-1806).
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Pre-CAT: Open-source tools for pre-clinical CEST-MRI data analysis
Published in ISMRM & ISMRT Annual Meeting and Exhibition, 2025
CEST is an emerging MRI technique capable of detecting small biochemical changes in vivo, providing valuable insights into the pathophysiology of various disease models; however, the lack of standardized tools for data processing complicates the sharing and interpretation of experimental results.
Recommended citation: Weigand-Whittier J, et al. (2025). "Pre-CAT: Open-source tools for pre-clinical CEST-MRI data analysis; Proceedings of the 32nd Annual Meeting of ISMRM.
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Comparison of CEST analysis in Z and 1/Z for exchange rate quantification in tissue-like systems
Published in Experimental Nuclear Magnetic Resonance Conference, 2026
Accurate estimations of exchange rates are crucial for the development of quantitative methods in chemical exchange saturation transfer (CEST). However, the exchange rates of key metabolites (e.g, creatine, glutamate) in biological tissue remain a source of debate within the CEST community. We demonstrate the utility of ultrafast Z-spectroscopy (UFZS) combined with Pseudo-Voigt fitting and 1/Z analysis for rapid and accurate quantification of exchange rates in tissue-like systems with multiple overlapping CEST pools and strong magnetization transfer effects. Additionally, we show that the estimation of proton volume fractions and exchange rates using the analytical “QUantification of Exchange rates using varying Saturation Powers” (QUESP) equations is highly dependent upon the method used for summing CEST contrasts, particularly in tissue-like systems.
talks
Talk 1 on Relevant Topic in Your Field
Published:
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Conference Proceeding talk 3 on Relevant Topic in Your Field
Published:
This is a description of your conference proceedings talk, note the different field in type. You can put anything in this field.
teaching
Engineering Devices I
Undergraduate course, UC Berkeley, Bioengineering, 2024
I served as a graduate student instructor for this course during the Fall 2024 semester. I prepared hour long weekly discussions to reinforce and expand upon material presented in class. I also held weekly office hours and exam review sessions. Other duties included: grading weekly problem sets and exams, designing exam problems, and providing feedback on students’ final design projects.
Biomedical Imaging Systems II: Targeted Molecular Imaging in Disease
Undergraduate/graduate course, UC Berkeley, Bioengineering, 2026
I served as a grader for this course during the Spring 2026 semester. My duties included: holding biweekly office hours to provide assistance with problem sets, holding informal discussions and journal club meetings, and providing feedback for final design projects.